Education
Ph.D. Organic Chemistry, Weizmann Institute of Science, 2003
Experience
Dr. Riki Goobes completed her postdoctoral studies at the department of Bioengineering at the University of Washington, Seattle, Washington. In her postdoctoral studies she investigated the structure of bio-molecules adsorbed onto synthetic and natural surfaces using various biophysical techniques such as nuclear magnetic resonance (NMR).
Riki is experienced in all areas of chemistry including: organic chemistry, inorganic chemistry, physical chemistry, chemical physics, chemistry of nucleic acids, surface chemistry, bio-mineralization, bio-technology, nano-technology, biochemistry, molecular biology, protein synthesis, isolation and structure elucidation of natural products.
Publications:
Goobes R, Rudi A, and Kashman Y. “Three new glycolipids from Red Sea sponge of the genus Erylus”. TETRAHEDRON. 1996, 52, 7921-7928.
Goobes R, Minsky A. “Contextual equilibrium effects in DNA molecules”. Biol. Chem. 2001, 276, 16155-60.
Goobes R, Minsky A. “Thermodynamic Aspects of Triplex DNA Formation in Crowded Environments“. J. Am. Chem. Soc. 2001, 123, 12692-12693.
Goobes R, Cohen O, and Minsky A. “Unique Condensation Patterns of Triplex DNA: Physical Aspects and Physiological Implications”. Acids Res. 2002, 30, 2154-2161.
Goobes R, Kahana N, Cohen O, and Minsky A. “Metabolic Buffering Exerted by Macromolecular Crowding on DNA-DNA interactions: Origin and Physiological Significance”. 2003, 42, 2431-2440.
Goobes R, Goobes G, Campbell C.T, Stayton P.S. “Thermodynamics of Statherin Adsorption onto Hydroxyapatite”. 2006, 45, 5576-5586.
Goobes G, Goobes R, Schueler-Furman O, Baker D, Stayton P.S, Drobny G.P. “Folding of the C-terminal bacterial binding domain in statherin upon adsorption onto hydroxyapatite crystals”, PNAS. 2006, 103, 16083-16088.
Goobes R, Goobes G, Shaw W.J, Campbell C.T, Drobny G.P, Stayton P.S. “Thermodynamic Roles of Basic Amino Acids in Statherin Recognition of Hydroxyapatite”, 2007, 46, 4725-4733.
Goobes G, Goobes R, Shaw W.J, Gibson J.M, Long J.R, Raghunathan V, Schueler-Furman O, Popham J.M, Baker D, Campbell C.T, Stayton P.S and Drobny G.P. “The Structure, Dynamics, and Energetics of Protein Adsorption – Lessons Learned from Adsorption of Statherin to Hydroxyapatite” Reson. Chem. 2007, 45, S32-47.